Everything about small fiber neuropathy



Neuropathy is a basic term signifying disturbances in the normal performance of the peripheral nerves. The reasons for neuropathy are different and so is the treatment. Lots of a times, the neuropathy is practically permanent and the treatment is mainly concentrated on avoiding additional progression of the nerve damage and other encouraging steps to prevent any issues due to neuropathy.

Neuropathies due to dietary deficiencies are mainly treated with the replenishment of the lacking nutrient. Neuropathies due to shortage of vitamins like cobalamin, thiamine, pyridoxine, niacin are treated by giving the vitamin supplements orally or by intramuscular injection of the vitamin if deficiency is due to malfunctioning absorption of vitamins from the diet plan. Treatment may or may not entirely reverse the neuropathy and minimize the symptoms and in most cases there is some long-term damage to nerves and consistent symptoms regardless of therapy. Recently neuropathy due to copper shortage has actually also been found. It too is treated with oral copper salts or intravenous injection of copper salts. Once again the response varies and might take numerous months.

Entrapment neuropathies like carpal tunnel syndrome, radial neuropathy, meralgia paraesthetica, etc are treated based on specific cause and the nerve included. Again, each neuropathy is special and treatment is variable.

The treatment of neuropathies secondary to other illness is the treatment of the primary illness causing the neuropathy. If neuropathy is due to Myxedema, triggered by lack of thyroid hormonal agent, then treatment is replacing the thyroid hormonal agent. Treatment of Diabetic Neuropathy is primarily helpful.

Treatment of neuropathy due to food allergy is preventing the allergen food product causing neuropathy. Neuropathy might also be because of harmful result of certain drugs like Chloroquine, Phenytoin, various others and anti-cancer drugs. Treatment in this case is generally discontinuation of the drug or dose decrease. There may be some particular treatment in certain cases, like neuropathy due to isoniazid can generally be prevented by offering pyridoxine along with it.


Many a times, the neuropathy is practically irreparable and the treatment is primarily focused on avoiding additional development of the nerve damage and other supportive procedures to prevent any problems due to neuropathy.

Entrapment neuropathies like carpal tunnel syndrome, radial neuropathy, meralgia paraesthetica, etc are treated based on particular cause and the nerve involved. The treatment of neuropathies secondary to other diseases is the treatment of the main disease triggering the neuropathy. Treatment of neuropathy due to food allergy is preventing the allergen food product causing neuropathy.

Whatever the original cause, your nerves reacted with the only survival tool they had: they contracted, they reduced their length and volume to protect themselves, and the spaces between the nerves(synapse) were stretched. A regular sized nerve signal could no longer jump this space. Thus nerve impulses, both those going up to the brain and those coming down from the brain were impaired.

Built-in microprocessors steps numerous physiological functions of your nerves and automatically adjusts itself to your particular therapeutic needs, starting with the first healing signal.

When the system is very first turned on, it determines the electrical analog resistance and digital impedance and sets its output criteria for your physical mass. It knows if it is treating a 125 pound female or a 350 lb guy. If you utilize it straight on your lower back, it knows that.

Specialized stimulator then sends out a "test" signal that represents the most common waveform for healthy peripheral nerves. This signal goes from one foot, up the leg, to the nerve roots in your lower back, down the other leg, to the other foot. It then awaits an echo-like response from this initial signal.
It then examines website this 'return" signal to determine any aberrations.

Just as a cardiologist can take one appearance at the shape of the signal displayed on an EKG screen, and detect what is wrong with the heart, we have actually been able to determine that the peripheral nerves have a really specific shape to its waveform. Therefore we can identify the nature of the problem by analyzing that waveform. This function is constructed into the stimulator and processed by its internal microprocessor.

Abnormalities in the shape of the waveform en route up shows issues with tingling; the shape of the top of the waveform shows the ability of the nerve to deliver the signal enough time for the brain to receive it all; irregularities in the down slope of the waveform indicates discomfort, and the shape of the refractory duration as the nerve cell repolarize's itself suggests the capability of the nerve path to prepare for the next signal.

The gadget needs to then create, and send, a compensating waveform, to 'ravel' these abnormalities, very much like the method noise canceling headphones work.

This procedure goes on 7.83 times every 2nd, sending a signal, evaluating the returning signal, developing a compensating signal, and sending this brand-new signal. It is constantly evaluating your action, and adjusting itself, to gently coax your nerve's capability to send out and receive proper signals.

These impulses are sent 7.83 times per second since that is how long it takes for the nerve cell to re-polarize (or reset) itself in between its transmission of nerve signals. Minerals like calcium, salt, and potassium must pass back and forth through the cell wall of the nerves. This is why a common TENS simply obstructs the nerve signals.

The signals, (as they cross the synaptic junctions in the nerve roots of the lower back to get from one leg to the other), create a small electro-magnetic field that is picked up by the nerves in your central nervous system (spine) and a signal is submitted to the brain to let it understand exactly what is happening in the lumbar area. The brain then launches endorphins, internal painkiller that travel via the blood stream to all parts of the body. These endorphins briefly ease discomfort in other parts of the body and aid elevate your mood. These endorphin modulated advantages are palliative, and last for about 4 hours, offerring extra welcome remedy for your peripheral neuropathy pain.


Whatever the initial cause, your nerves reacted with the only survival tool they had: they contracted, they reduced their length and volume to preserve themselves, and the gaps between the nerves(synapse) were extended. A regular sized nerve signal might no longer leap this gap. Specialized stimulator then sends out a "test" signal that represents the most common waveform for healthy peripheral nerves. These impulses are sent 7.83 times per second since that is how long it takes for the nerve cell to re-polarize (or reset) itself in between its transmission of nerve signals. The signals, (as they cross the synaptic junctions in the nerve roots of the lower back to get from one leg to the other), develop a little electromagnetic field that is sensed by the nerves in your central anxious system (spinal column) and a signal is submitted to the brain to let it understand exactly what is taking place in the lumbar area.

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